Perspectives on Vancomycin Use in Home Care
Current literature supports the conclusion that there is no direct correlation between vancomycin concentration or rate of administration and side effects (particularly red man syndrome). Venous access devices such as midclavicular catheters, midlines, and peripheral inserted central catheters (PICCs) enable more concentrated solutions of vancomycin to be infused safely without an increased incidence of adverse events.
Pharmacologic Characteristics of Vancomycin Vancomycin is derived from the bacterium Streptomyces orientalis, which was isolated from the soil of India and Indonesia in 1956. 5-7 Since 1958, it has been used to treat gram-positive bacterial infections (specifically those produced by staphylococci and enterococci). It is particularly effective against methicillin-resistant Staphylococcus aureus (MRSA), which is a prevalent nosocomial pathogen in the United States.
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http://www.clinicaliq.com/content/vanco.pdf
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